Codonopsis lanceolata attenuates allergic lung inflammation by inhibiting Th2 cell activation and augmenting mitochondrial ROS dismutase (SOD2) expression
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چکیده
منابع مشابه
Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction
A single treatment with a CpG-containing immunostimulatory DNA sequence (ISS) given before allergen challenge can inhibit T helper type 2 cell (Th2)-mediated airway responses in animal models of allergic asthma; however, the mechanism of this inhibition remains largely undefined. Here, we demonstrate that airway delivery of ISS before allergen challenge in Th2-primed mice acts in two distinct w...
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متن کاملAnaphylactic shock induced by Codonopsis lanceolata, traditional Chinese medicine in a patient with allergic rhinitis.
Codonopsis lanceolata (CL) contains various active components including tannins, saponins, polyphenolics, alkaloids, essential oils and steroids. Therefore, it has been prescribed as a traditional folk medicine to treat several inflammatory diseases (1, 2). To date, there have been no published reports of allergic reactions to CL. In this report, we present a serious anaphylactoid reaction foll...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-019-38782-6